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Title:

The exercise IL-6 enigma in cancer

Document type:
Zeitschriftenaufsatz
Author(s):
Orange, Samuel T.; Leslie, Jack; Ross, Mark; Mann, Derek A.; Wackerhage, Henning
Abstract:
Interleukin (IL)-6 elicits both anticancer and procancer effects depending on the context, which we have termed the ‘exercise IL-6 enigma’. IL-6 is released from skeletal muscles during exercise to regulate short-term energy availability. Exercise-induced IL-6 provokes biological effects that may protect against cancer by improving insulin sensitivity, stimulating the production of anti-inflammatory cytokines, mobilising immune cells, and reducing DNA damage in early malignant cells. By contrast...     »
Dewey Decimal Classification:
610 Medizin und Gesundheit
Journal title:
Trends in Endocrinology & Metabolism
Year:
2023
Journal volume:
34
Year / month:
2023-11
Quarter:
4. Quartal
Month:
Nov
Journal issue:
11
Pages contribution:
749-763
Covered by:
Web of Science
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.1016/j.tem.2023.08.001
Publisher:
Elsevier BV
E-ISSN:
1043-2760
Impact Factor:
10,9
Scimago Quartil:
Q1
Notes:
SCImago Journal &  Country Rank
Date of publication:
01.11.2023
Semester:
WS 23-24
TUM Institution:
Sportbiologie
Format:
Bild/Text
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