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Title:

The exercise IL-6 enigma in cancer

Document type:
Zeitschriftenaufsatz
Author(s):
Orange, Samuel T.; Leslie, Jack; Ross, Mark; Mann, Derek A.; Wackerhage, Henning
Abstract:
Interleukin (IL)-6 elicits both anticancer and procancer effects depending on the context, which we have termed the ‘exercise IL-6 enigma’. IL-6 is released from skeletal muscles during exercise to regulate short-term energy availability. Exercise-induced IL-6 provokes biological effects that may protect against cancer by improving insulin sensitivity, stimulating the production of anti-inflammatory cytokines, mobilising immune cells, and reducing DNA damage in early malignant cells. By contrast...     »
Keywords:
cancer, interleuki-6, exercise
Dewey Decimal Classification:
500 Naturwissenschaften; 570 Biowissenschaften, Biologie; 610 Medizin und Gesundheit
Journal title:
Trends in Endocrinology & Metabolism
Year:
2023
Year / month:
2023-08
Quarter:
3. Quartal
Month:
Aug
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.1016/j.tem.2023.08.001
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37633799
WWW:
https://www.sciencedirect.com/science/article/pii/S1043276023001546
Publisher:
Elsevier BV
E-ISSN:
1043-2760
Impact Factor:
2,3
Scimago Quartil:
Q1
Notes:
SCImago Journal &  Country Rank
Status:
Erstveröffentlichung
Date of publication:
01.08.2023
Semester:
SS 23
TUM Institution:
Sportbiologie
Format:
Bild/Text
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