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Title:

The role of intrathecal free light chains kappa for the detection of autoimmune encephalitis in subacute onset neuropsychiatric syndromes.

Document type:
Article; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Bertram, Dominic; Tsaktanis, Thanos; Berthele, Achim; Korn, Thomas
Abstract:
Intrathecal synthesis of free light chains kappa (FLCK) is increasingly recognized as a marker of inflammatory CNS pathologies. Here, we tested the performance of FLCK in differentiating autoimmune encephalitis (AIE) from non-inflammatory etiologies in subacute onset neuropsychiatric syndromes. Patients undergoing diagnostic work-up for suspected autoimmune encephalitis at our department between 2015 and 2020 were retrospectively assessed for definitive diagnosis, available CSF and blood samples...     »
Journal title abbreviation:
Sci Rep
Year:
2023
Journal volume:
13
Journal issue:
1
Fulltext / DOI:
doi:10.1038/s41598-023-44427-6
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37821561
Print-ISSN:
2045-2322
TUM Institution:
Klinik und Poliklinik für Neurologie (Prof. Hemmer); Molekulare Immunologie (Prof. Knolle)
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