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Title:

Efficacy of human C1 esterase inhibitor concentrate for treatment of ACE-inhibitor induced angioedema.

Document type:
Article; Journal Article
Author(s):
Strassen, Ulrich; Bas, Murat; Wirth, Magdalena; Wirth, Markus; Gröger, Moritz; Stelter, Klaus; Volkenstein, Stefan; Kehl, Victoria; Kojda, Georg; Hoffmann, Thomas K; Hahn, Janina; Trainotti, Susanne; Greve, Jens
Abstract:
BACKGROUND: ACE inhibitor (ACEi) induced angioedema predominantly affects the upper aerodigestive tract. As ACEi induced angioedema is mediated by bradykinin, therapeutic response to antihistamines and glucocorticoids remains unsatisfactory. In bradykinin mediated hereditary angioedema, C1-esterase inhibitor (C1INH) is an effective and approved treatment since many years. Our aim was to evaluate the therapeutic effect of C1INH in ACEi induced angioedema. METHODS: We performed a double-blind, par...     »
Journal title abbreviation:
Am J Emerg Med
Year:
2023
Journal volume:
64
Pages contribution:
121-128
Fulltext / DOI:
doi:10.1016/j.ajem.2022.12.001
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36516670
Print-ISSN:
0735-6757
TUM Institution:
1141; 1212; 284; 599; Departments; Institut für KI und Informatik in der Medizin (Prof. Rückert); Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde (Prof. Wollenberg); Lehrstuhl für Medizinische Informatik (Prof. Boeker)
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