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Titel:

Comparison of PD-L1 expression in squamous cell cancer of unknown primary and oropharyngeal squamous cell carcinoma.

Dokumenttyp:
Journal Article
Autor(en):
Schmidl, Benedikt; Voßenkämper, Kim-Aylin; Stark, Leonhard; Boxberg, Melanie; Stögbauer, Fabian; Feigl, Katharina; Winter, Christof; Pickhard, Anja; Wollenberg, Barbara; Wirth, Markus
Abstract:
PURPOSE: The tumorigenesis of squamous cell cancer of unknown primary (SCCUP) in the head and neck area has not been decoded so far, while poor survival rates and limited therapeutic options pose a serious challenge. The aim of this project was to investigate immunological characteristics of SCCUPs and compare them to oropharyngeal squamous cell carcinoma (OPSCC). METHODS: PD-L1 expression (TC) was examined by immunohistochemistry in 50 lymph node metastases of SCCUP and 47 primaries of OPSCC. C...     »
Zeitschriftentitel:
Eur Arch Otorhinolaryngol
Jahr:
2023
Band / Volume:
280
Heft / Issue:
4
Seitenangaben Beitrag:
1991-1997
Volltext / DOI:
doi:10.1007/s00405-022-07775-z
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36576530
Print-ISSN:
0937-4477
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.); Institut für Klinische Chemie und Pathobiochemie (Prof. Ruland); Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde (Prof. Wollenberg)
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