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Title:

CLEC12A Binds to Legionella pneumophila but Has No Impact on the Host's Antibacterial Response.

Document type:
Journal Article
Author(s):
Klatt, Ann-Brit; Diersing, Christina; Lippmann, Juliane; Mayer-Lambertz, Sabine; Stegmann, Felix; Fischer, Swantje; Caesar, Sandra; Fiocca Vernengo, Facundo; Hönzke, Katja; Hocke, Andreas C; Ruland, Jürgen; Witzenrath, Martin; Lepenies, Bernd; Opitz, Bastian
Abstract:
Legionella pneumophila is an intracellular pathogen that can cause severe pneumonia after the inhalation of contaminated aerosols and replication in alveolar macrophages. Several pattern recognition receptors (PRRs) have been identified that contribute to the recognition of L. pneumophila by the innate immune system. However, the function of the C-type lectin receptors (CLRs), which are mainly expressed by macrophages and other myeloid cells, remains largely unexplored. Here, we used a library o...     »
Journal title abbreviation:
Int J Mol Sci
Year:
2023
Journal volume:
24
Journal issue:
4
Fulltext / DOI:
doi:10.3390/ijms24043891
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36835297
Print-ISSN:
1422-0067
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie (Prof. Ruland)
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