Benutzer: Gast  Login
Titel:

IFN-1s: Sentinels Shaping Distinct Immune Responses in Skin.

Dokumenttyp:
Journal Article; Comment
Autor(en):
Garzorz-Stark, Natalie; Eyerich, Kilian
Abstract:
IFN-1s are early sentinels of potential danger in skin. Two interconnected axes exist: plasmacytoid dendritic cells (DCs) secreting IFN-α in response to single strand RNA or DNA and keratinocytes secreting IFN-κ after stimulation with double strand RNA or other IFNs. Both IFN-α and IFN-κ induce macrophages and DC subpopulations to secrete master regulators of cytotoxicity or wound healing, the latter related to psoriasis pathogenesis.
Zeitschriftentitel:
J Invest Dermatol
Jahr:
2022
Band / Volume:
142
Heft / Issue:
1
Seitenangaben Beitrag:
14-15
Volltext / DOI:
doi:10.1016/j.jid.2021.07.161
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34565563
Print-ISSN:
0022-202X
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie
 BibTeX