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Titel:

The long non-coding RNA NRON promotes the development of cardiac hypertrophy in the murine heart.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Hoepfner, Jeannine; Leonardy, Julia; Lu, Dongchao; Schmidt, Kevin; Hunkler, Hannah J; Biß, Sinje; Foinquinos, Ariana; Xiao, Ke; Regalla, Kumarswamy; Ramanujam, Deepak; Engelhardt, Stefan; Bär, Christian; Thum, Thomas
Abstract:
Physiological and pathological cardiovascular processes are tightly regulated by several cellular mechanisms. Non-coding RNAs, including long non-coding RNAs (lncRNAs), represent one important class of molecules involved in regulatory processes within the cell. The lncRNA non-coding repressor of NFAT (NRON) was described as a repressor of the nuclear factor of activated T cells (NFAT) in different in vitro studies. Although the calcineurin/NFAT-signaling pathway is one of the most important path...     »
Zeitschriftentitel:
Mol Ther
Jahr:
2022
Band / Volume:
30
Heft / Issue:
3
Seitenangaben Beitrag:
1265-1274
Volltext / DOI:
doi:10.1016/j.ymthe.2021.11.018
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34856383
Print-ISSN:
1525-0016
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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