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Title:

Reporter gene-based optoacoustic imaging of E. coli targeted colon cancer in vivo.

Document type:
Zeitschriftenaufsatz
Author(s):
Yun, Misun; You, Sung-Hwan; Nguyen, Vu Hong; Prakash, Jaya; Glasl, Sarah; Gujrati, Vipul; Choy, Hyon E; Stiel, Andre C; Min, Jung-Joon; Ntziachristos, Vasilis
Abstract:
Bacteria-mediated cancer-targeted therapy is a novel experimental strategy for the treatment of cancers. Bacteria can be engineered to overcome a major challenge of existing therapeutics by differentiating between malignant and healthy tissue. A prerequisite for further development and study of engineered bacteria is a suitable imaging concept which allows bacterial visualization in tissue and monitoring bacterial targeting and proliferation. Optoacoustics (OA) is an evolving technology allowing...     »
Journal title:
Scientific Reports
Journal title abbreviation:
Sci Rep
Year:
2021
Journal volume:
11
Journal issue:
1
Fulltext / DOI:
doi:10.1038/s41598-021-04047-4
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34952915
WWW:
https://www.nature.com/articles/s41598-021-04047-4
Print-ISSN:
2045-2322
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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