Benutzer: Gast  Login
Titel:

Comparative analysis of extracellular vesicle isolation methods from human AML bone marrow cells and AML cell lines.

Dokumenttyp:
Article; Journal Article
Autor(en):
Lang, Jonas B; Buck, Michèle C; Rivière, Jennifer; Stambouli, Oumaima; Sachenbacher, Ken; Choudhary, Purva; Dietz, Hendrik; Giebel, Bernd; Bassermann, Florian; Oostendorp, Robert A J; Götze, Katharina S; Hecker, Judith S
Abstract:
Cellular crosstalk between hematopoietic stem/progenitor cells and the bone marrow (BM) niche is vital for the development and maintenance of myeloid malignancies. These compartments can communicate via bidirectional transfer of extracellular vesicles (EVs). EV trafficking in acute myeloid leukemia (AML) plays a crucial role in shaping the BM microenvironment into a leukemia-permissive niche. Although several EV isolation methods have been developed, it remains a major challenge to define the mo...     »
Zeitschriftentitel:
Front Oncol
Jahr:
2022
Band / Volume:
12
Volltext / DOI:
doi:10.3389/fonc.2022.949261
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36263223
Print-ISSN:
2234-943X
TUM Einrichtung:
Klinik und Poliklinik für Innere Medizin III, Hämatologie und Onkologie
 BibTeX