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Title:

MbnC Is Not Required for the Formation of the N-Terminal Oxazolone in the Methanobactin from Methylosinus trichosporium OB3b.

Document type:
Journal Article
Author(s):
Dershwitz, Philip; Gu, Wenyu; Roche, Julien; Kang-Yun, Christina S; Semrau, Jeremy D; Bobik, Thomas A; Fulton, Bruce; Zischka, Hans; DiSpirito, Alan A
Abstract:
Methanobactins (MBs) are ribosomally synthesized and posttranslationally modified peptides (RiPPs) produced by methanotrophs for copper uptake. The posttranslational modification that defines MBs is the formation of two heterocyclic groups with associated thioamines from X-Cys dipeptide sequences. Both heterocyclic groups in the MB from Methylosinus trichosporium OB3b (MB-OB3b) are oxazolone groups. The precursor gene for MB-OB3b is mbnA, which is part of a gene cluster that contains both annota...     »
Journal title abbreviation:
Appl Environ Microbiol
Year:
2022
Journal volume:
88
Journal issue:
2
Fulltext / DOI:
doi:10.1128/AEM.01841-21
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34731053
Print-ISSN:
0099-2240
TUM Institution:
Institut für Toxikologie und Umwelthygiene
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