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Titel:

Current State of Immunotherapy and Mechanisms of Immune Evasion in Ewing Sarcoma and Osteosarcoma.

Dokumenttyp:
Journal Article; Review
Autor(en):
Evdokimova, Valentina; Gassmann, Hendrik; Radvanyi, Laszlo; Burdach, Stefan E G
Abstract:
We argue here that in many ways, Ewing sarcoma (EwS) is a unique tumor entity and yet, it shares many commonalities with other immunologically cold solid malignancies. From the historical perspective, EwS, osteosarcoma (OS) and other bone and soft-tissue sarcomas were the first types of tumors treated with the immunotherapy approach: more than 100 years ago American surgeon William B. Coley injected his patients with a mixture of heat-inactivated bacteria, achieving survival rates apparently hig...     »
Zeitschriftentitel:
Cancers (Basel)
Jahr:
2022
Band / Volume:
15
Heft / Issue:
1
Volltext / DOI:
doi:10.3390/cancers15010272
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36612267
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Kinder- und Jugendmedizin
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