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Title:

Associations of medication with subcortical morphology across the lifespan in OCD: Results from the international ENIGMA Consortium.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Author(s):
Ivanov, Iliyan; Boedhoe, Premika S W; Abe, Yoshinari; Alonso, Pino; Ameis, Stephanie H; Arnold, Paul D; Balachander, Srinivas; Baker, Justin T; Banaj, Nerisa; Bargalló, Nuria; Batistuzzo, Marcelo C; Benedetti, Francesco; Beucke, Jan C; Bollettini, Irene; Brem, Silvia; Brennan, Brian P; Buitelaar, Jan; Calvo, Rosa; Cheng, Yuqi; Cho, Kang Ik K; Dallaspezia, Sara; Denys, Damiaan; Diniz, Juliana B; Ely, Benjamin A; Feusner, Jamie D; Ferreira, Sónia; Fitzgerald, Kate D; Fontaine, Martine; Gruner, Pat...     »
Abstract:
BACKGROUND: Widely used psychotropic medications for obsessive-compulsive disorder (OCD) may change the volumes of subcortical brain structures, and differently in children vs. adults. We measured subcortical volumes cross-sectionally in patients finely stratified for age taking various common classes of OCD drugs. METHODS: The ENIGMA-OCD consortium sample (1081 medicated/1159 unmedicated OCD patients and 2057 healthy controls aged 6-65) was divided into six successive 6-10-year age-groups. Indi...     »
Journal title abbreviation:
J Affect Disord
Year:
2022
Journal volume:
318
Pages contribution:
204-216
Fulltext / DOI:
doi:10.1016/j.jad.2022.08.084
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36041582
Print-ISSN:
0165-0327
TUM Institution:
Professur für Neuroradiologie (Prof. Zimmer)
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