Introducing nuclei scatterer patterns into histology-based intravascular ultrasound simulation framework

We introduce a framework to simulate intravascular ultrasound (IVUS) from histological sections. These sections were previously acquired along with real IVUS radiofrequency signals using single-element 40MHz transducer. After labeling and registering the section to the corresponding IVUS image, a virtual phantom was created, incorporating nuclei scatterer patterns. A finite differences simulation of the acoustic signal was performed, resulting in backscattered radiofrequency signals. These were used to process a B-mode image, which in turn was compared to the real IVUS image of the same section. A high image quality with a very promising correlation to the original IVUS images was achieved.     «

We introduce a framework to simulate intravascular ultrasound (IVUS) from histological sections. These sections were previously acquired along with real IVUS radiofrequency signals using single-element 40MHz transducer. After labeling and registering the section to the corresponding IVUS image, a virtual phantom was created, incorporating nuclei scatterer patterns. A finite differences simulation of the acoustic signal was performed, resulting in backscattered radiofrequency signals. These were...     »