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Titel:

Animal models of arrhythmia: classic electrophysiology to genetically modified large animals.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review; Review
Autor(en):
Clauss, Sebastian; Bleyer, Christina; Schüttler, Dominik; Tomsits, Philipp; Renner, Simone; Klymiuk, Nikolai; Wakili, Reza; Massberg, Steffen; Wolf, Eckhard; Kääb, Stefan
Abstract:
Arrhythmias are common and contribute substantially to cardiovascular morbidity and mortality. The underlying pathophysiology of arrhythmias is complex and remains incompletely understood, which explains why mostly only symptomatic therapy is available. The evaluation of the complex interplay between various cell types in the heart, including cardiomyocytes from the conduction system and the working myocardium, fibroblasts and cardiac immune cells, remains a major challenge in arrhythmia researc...     »
Zeitschriftentitel:
Nat Rev Cardiol
Jahr:
2019
Band / Volume:
16
Heft / Issue:
8
Seitenangaben Beitrag:
457-475
Volltext / DOI:
doi:10.1038/s41569-019-0179-0
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30894679
Print-ISSN:
1759-5002
TUM Einrichtung:
1693; Klinik und Poliklinik für Innere Medizin I, Kardiologie
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