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Titel:

The transmembrane protein LRIG1 triggers melanocytic tumor development following chemically induced skin carcinogenesis.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Hoesl, Christine; Fröhlich, Thomas; Posch, Christian; Kneitz, Hermann; Goebeler, Matthias; Schneider, Marlon R; Dahlhoff, Maik
Abstract:
The incidence of melanoma and nonmelanoma skin cancer has increased tremendously in recent years. Although novel treatment options have significantly improved patient outcomes, the prognosis for most patients with an advanced disease remains dismal. It is, thus, imperative to understand the molecular mechanisms involved in skin carcinogenesis in order to develop new targeted treatment strategies. Receptor tyrosine kinases (RTK) like the ERBB receptor family, including EGFR/ERBB1, ERBB2/NEU, ERBB...     »
Zeitschriftentitel:
Mol Oncol
Jahr:
2021
Band / Volume:
15
Heft / Issue:
8
Seitenangaben Beitrag:
2140-2155
Volltext / DOI:
doi:10.1002/1878-0261.12945
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33786987
Print-ISSN:
1574-7891
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie
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