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Title:

The transmembrane protein LRIG1 triggers melanocytic tumor development following chemically induced skin carcinogenesis.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Hoesl, Christine; Fröhlich, Thomas; Posch, Christian; Kneitz, Hermann; Goebeler, Matthias; Schneider, Marlon R; Dahlhoff, Maik
Abstract:
The incidence of melanoma and nonmelanoma skin cancer has increased tremendously in recent years. Although novel treatment options have significantly improved patient outcomes, the prognosis for most patients with an advanced disease remains dismal. It is, thus, imperative to understand the molecular mechanisms involved in skin carcinogenesis in order to develop new targeted treatment strategies. Receptor tyrosine kinases (RTK) like the ERBB receptor family, including EGFR/ERBB1, ERBB2/NEU, ERBB...     »
Journal title abbreviation:
Mol Oncol
Year:
2021
Journal volume:
15
Journal issue:
8
Pages contribution:
2140-2155
Fulltext / DOI:
doi:10.1002/1878-0261.12945
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/33786987
Print-ISSN:
1574-7891
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie
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