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Titel:

Contribution of D1R-expressing neurons of the dorsal dentate gyrus and Cav1.2 channels in extinction of cocaine conditioned place preference.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Autor(en):
Burgdorf, Caitlin E; Bavley, Charlotte C; Fischer, Delaney K; Walsh, Alexander P; Martinez-Rivera, Arlene; Hackett, Jonathan E; Zallar, Lia J; Ireton, Kyle E; Hofmann, Franz; Hell, Johannes W; Huganir, Richard L; Rajadhyaksha, Anjali M
Abstract:
Cocaine-associated contextual cues can trigger relapse behavior by recruiting the hippocampus. Extinction of cocaine-associated contextual memories can reduce cocaine-seeking behavior, however the molecular mechanisms within the hippocampus that underlie contextual extinction behavior and subsequent reinstatement remain poorly understood. Here, we extend our previous findings for a role of Cav1.2 L-type Ca2+ channels in dopamine 1 receptor (D1R)-expressing cells in extinction of cocaine conditio...     »
Zeitschriftentitel:
Neuropsychopharmacology
Jahr:
2020
Band / Volume:
45
Heft / Issue:
9
Seitenangaben Beitrag:
1506-1517
Volltext / DOI:
doi:10.1038/s41386-019-0597-z
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31905369
Print-ISSN:
0893-133X
TUM Einrichtung:
Institut für Pharmakologie und Toxikologie
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