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Titel:

Preanalytical variables that affect the outcome of cell-free DNA measurements.

Dokumenttyp:
Review; Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Ungerer, Vida; Bronkhorst, Abel J; Holdenrieder, Stefan
Abstract:
Fragments of cell-free DNA (cfDNA) in human body fluids often carry disease-specific alterations and are now widely recognized as ideal biomarkers for the detection and monitoring of genomic disorders, especially cancer, that are normally difficult to examine noninvasively. However, the conversion of promising research findings into tools useful in routine clinical testing of cancer has been a slow-moving process. A major reason is that the diagnostic sensitivity and specificity of cfDNA-based c...     »
Zeitschriftentitel:
Crit Rev Clin Lab Sci
Jahr:
2020
Band / Volume:
57
Heft / Issue:
7
Seitenangaben Beitrag:
484-507
Volltext / DOI:
doi:10.1080/10408363.2020.1750558
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32393081
Print-ISSN:
1040-8363
TUM Einrichtung:
Institut für Laboratoriumsmedizin (keine SAP-Zuordnung!)
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