Sander, Paulina;Feng, Michael;Schweitzer, Maria K;Wilting, Fabiola;Gutenthaler, Sophie M;Arduino, Daniela M;Fischbach, Sandra;Dreizehnter, Lisa;Moretti, Alessandra;Gudermann, Thomas;Perocchi, Fabiana;Schredelseker, Johann
Approved drugs ezetimibe and disulfiram enhance mitochondrial Ca2+ uptake and suppress cardiac arrhythmogenesis.
Br J Pharmacol
2021
178
22
4518-4532

Fomin, Andrey;Gärtner, Anna;Cyganek, Lukas;Tiburcy, Malte;Tuleta, Izabela;Wellers, Luisa;Folsche, Lina;Hobbach, Anastasia J;von Frieling-Salewsky, Marion;Unger, Andreas;Hucke, Anna;Koser, Franziska;Kassner, Astrid;Sielemann, Katharina;Streckfuß-Bömeke, Katrin;Hasenfuss, Gerd;Goedel, Alexander;Laugwitz, Karl-Ludwig;Moretti, Alessandra;Gummert, Jan F;Dos Remedios, Cristobal G;Reinecke, Holger;Knöll, Ralph;van Heesch, Sebastiaan;Hubner, Norbert;Zimmermann, Wolfram H;Milting, Hendrik;Linke, Wolfgang A
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations.
Sci Transl Med
2021
13
618

Zhang, Fangfang;Meier, Anna B;Laugwitz, Karl-Ludwig;Dorn, Tatjana;Moretti, Alessandra
Generation of heterozygous (MRli003-A-1) and homozygous (MRli003-A-2) MYH10 knockout human iPSC lines.
Stem Cell Res
2021
57

Besikcioglu, H Erdinc;Yurteri, Ümmügülsüm;Munkhbaatar, Enkhtsetseg;Ye, Linhan;Zhang, Fangfang;Moretti, Alessandra;Mota Reyes, Carmen;Özoğul, Candan;Friess, Helmut;Ceyhan, Güralp O;Istvanffy, Rouzanna;Demir, Ihsan Ekin
Innervated mouse pancreas organoids as an ex vivo model to study pancreatic neuropathy in pancreatic cancer.
STAR Protoc
2021
2
4

Lu, Kun;Seidel, Thomas;Cao-Ehlker, Xiaochun;Dorn, Tatjana;Batcha, Aarif Mohamed Nazeer;Schneider, Christine Maria;Semmler, Marie;Volk, Tilmann;Moretti, Alessandra;Dendorfer, Andreas;Tomasi, Roland
Progressive stretch enhances growth and maturation of 3D stem-cell-derived myocardium.
Theranostics
2021
11
13
6138-6153

Krane, Markus;Dreßen, Martina;Santamaria, Gianluca;My, Ilaria;Schneider, Christine M;Dorn, Tatjana;Laue, Svenja;Mastantuono, Elisa;Berutti, Riccardo;Rawat, Hilansi;Gilsbach, Ralf;Schneider, Pedro;Lahm, Harald;Schwarz, Sascha;Doppler, Stefanie A;Paige, Sharon;Puluca, Nazan;Doll, Sophia;Neb, Irina;Brade, Thomas;Zhang, Zhong;Abou-Ajram, Claudia;Northoff, Bernd;Holdt, Lesca M;Sudhop, Stefanie;Sahara, Makoto;Goedel, Alexander;Dendorfer, Andreas;Tjong, Fleur V Y;Rijlaarsdam, Maria E;Cleuziou, Julie;Lang, Nora;Kupatt, Christian;Bezzina, Connie;Lange, Rüdiger;Bowles, Neil E;Mann, Matthias;Gelb, Bruce D;Crotti, Lia;Hein, Lutz;Meitinger, Thomas;Wu, Sean;Sinnecker, Daniel;Gruber, Peter J;Laugwitz, Karl-Ludwig;Moretti, Alessandra
Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome.
Circulation
2021
144
17
1409-1428

Hinkel, Rabea;Batkai, Sandor;Bähr, Andrea;Bozoglu, Tarik;Straub, Sarah;Borchert, Tobias;Viereck, Janika;Howe, Andrea;Hornaschewitz, Nadja;Oberberger, Lisa;Jurisch, Victoria;Kozlik-Feldmann, Rainer;Freudenthal, Franz;Ziegler, Tilman;Weber, Christian;Sperandio, Markus;Engelhardt, Stefan;Laugwitz, Karl Ludwig;Moretti, Alessandra;Klymiuk, Nik;Thum, Thomas;Kupatt, Christian
AntimiR-132 Attenuates Myocardial Hypertrophy in an Animal Model of Percutaneous Aortic Constriction.
J Am Coll Cardiol
2021
77
23
2923-2935

Brandes, Ralf P;Dueck, Anne;Engelhardt, Stefan;Kaulich, Manuel;Kupatt, Christian;De Angelis, Maria Teresa;Leisegang, Matthias S;le Noble, Ferdinand;Moretti, Alessandra;Müller, Oliver J;Skryabin, Boris V;Thum, Thomas;Wurst, Wolfgang
DGK and DZHK position paper on genome editing: basic science applications and future perspective.
Basic Res Cardiol
2021
116
1

Kupatt, Christian;Windisch, Alina;Moretti, Alessandra;Wolf, Eckhard;Wurst, Wolfgang;Walter, Maggie C
Genome editing for Duchenne muscular dystrophy: a glimpse of the future?
Gene Ther
2021
28
9
542-548

Parrotta, Elvira Immacolata;Procopio, Anna;Scalise, Stefania;Esposito, Claudia;Nicoletta, Giovanni;Santamaria, Gianluca;De Angelis, Maria Teresa;Dorn, Tatjana;Moretti, Alessandra;Laugwitz, Karl-Ludwig;Montefusco, Francesco;Cosentino, Carlo;Cuda, Giovanni
Deciphering the Role of Wnt and Rho Signaling Pathway in iPSC-Derived ARVC Cardiomyocytes by In Silico Mathematical Modeling.
Int J Mol Sci
2021
22
4