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Title:

A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.

Document type:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Author(s):
Kollmus, Heike; Fuchs, Helmut; Lengger, Christoph; Haselimashhadi, Hamed; Bogue, Molly A; Östereicher, Manuela A; Horsch, Marion; Adler, Thure; Aguilar-Pimentel, Juan Antonio; Amarie, Oana Veronica; Becker, Lore; Beckers, Johannes; Calzada-Wack, Julia; Garrett, Lillian; Hans, Wolfgang; Hölter, Sabine M; Klein-Rodewald, Tanja; Maier, Holger; Mayer-Kuckuk, Philipp; Miller, Gregor; Moreth, Kristin; Neff, Frauke; Rathkolb, Birgit; Rácz, Ildikó; Rozman, Jan; Spielmann, Nadine; Treise, Irina; Busch, D...     »
Abstract:
The collaborative cross (CC) is a large panel of mouse-inbred lines derived from eight founder strains (NOD/ShiLtJ, NZO/HILtJ, A/J, C57BL/6J, 129S1/SvImJ, CAST/EiJ, PWK/PhJ, and WSB/EiJ). Here, we performed a comprehensive and comparative phenotyping screening to identify phenotypic differences and similarities between the eight founder strains. In total, more than 300 parameters including allergy, behavior, cardiovascular, clinical blood chemistry, dysmorphology, bone and cartilage, energy meta...     »
Journal title abbreviation:
Mamm Genome
Year:
2020
Journal volume:
31
Journal issue:
1-2
Pages contribution:
30-48
Fulltext / DOI:
doi:10.1007/s00335-020-09827-3
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32060626
Print-ISSN:
0938-8990
TUM Institution:
617; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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