User: Guest  Login
Title:

Mediated Ablation of Conventional Dendritic Cells Suggests a Lymphoid Path to Generating Dendritic Cells .

Document type:
Journal Article; Article
Author(s):
Salvermoser, Johanna; van Blijswijk, Janneke; Papaioannou, Nikos E; Rambichler, Stephan; Pasztoi, Maria; Pakalni?kyt?, Dalia; Rogers, Neil C; Keppler, Selina J; Straub, Tobias; Reis E Sousa, Caetano; Schraml, Barbara U
Abstract:
Conventional dendritic cells (cDCs) are versatile activators of immune responses that develop as part of the myeloid lineage downstream of hematopoietic stem cells. We have recently shown that in mice precursors of cDCs, but not of other leukocytes, are marked by expression of DNGR-1/CLEC9A. To genetically deplete DNGR-1-expressing cDC precursors and their progeny, we crossed mice to Rosa-lox-STOP-lox-diphtheria toxin (DTA) mice. These mice develop signs of age-dependent myeloproliferative dise...     »
Journal title abbreviation:
Front Immunol
Year:
2018
Journal volume:
9
Pages contribution:
699
Fulltext / DOI:
doi:10.3389/fimmu.2018.00699
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29713321
Print-ISSN:
1664-3224
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie
 BibTeX