User: Guest  Login
Title:

Visualizing cortical response to optogenetic stimulation and sensory inputs using multispectral handheld optoacoustic imaging.

Document type:
Zeitschriftenaufsatz
Author(s):
Ovsepian, Saak V; Jiang, Yuanyuan; Sardella, Thomas C P; Malekzadeh-Najafabadi, Jaber; Burton, Neal C; Yu, Xin; Ntziachristos, Vasilis
Abstract:
To date, the vast majority of intra-vital neuroimaging systems applied in clinic and diagnostics is stationary with a rigid scanning element, requires specialized facilities and costly infrastructure. Here, we describe a simple yet radical approach for optoacoustic (photoacoustic) brain imaging in vivo using a light-weight handheld probe. It enables multispectral video-rate visualization of hemoglobin gradient changes in the cortex of adult rats induced by whisker and forelimb sensory inputs, as...     »
Journal title:
Photoacoustics
Journal title abbreviation:
Photoacoustics
Year:
2020
Journal volume:
17
Fulltext / DOI:
doi:10.1016/j.pacs.2019.100153
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32154103
WWW:
https://www.sciencedirect.com/science/article/pii/S221359791930076X
Print-ISSN:
2213-5979
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
 BibTeX