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Title:

Targeting Endothelin Receptors in a Murine Model of Myocardial Infarction Using a Small Molecular Fluorescent Probe.

Document type:
Zeitschriftenaufsatz
Author(s):
Kimm, Melanie A; Haas, Helena; Stölting, Miriam; Kuhlmann, Michael; Geyer, Christiane; Glasl, Sarah; Schäfers, Michael; Ntziachristos, Vasilis; Wildgruber, Moritz; Höltke, Carsten
Abstract:
The endothelin (ET) axis plays a pivotal role in cardiovascular diseases. Enhanced levels of circulating ET-1 have been correlated with an inferior clinical outcome after myocardial infarction (MI) in humans. Thus, the evaluation of endothelin-A receptor (ETAR) expression over time in the course of myocardial injury and healing may offer valuable information toward the understanding of the ET axis involvement in MI. We developed an approach to track the expression of ETAR with a customized molec...     »
Journal title:
Molecular Pharmaceutics
Journal title abbreviation:
Mol Pharm
Year:
2020
Journal volume:
17
Journal issue:
1
Pages contribution:
109-117
Fulltext / DOI:
doi:10.1021/acs.molpharmaceut.9b00810
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31816245
WWW:
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.9b00810
Print-ISSN:
1543-8384
TUM Institution:
Institut für Diagnostische und Interventionelle Radiologie; Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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