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Title:

Deep tissue volumetric optoacoustic tracking of individual circulating tumor cells in an intracardially perfused mouse model.

Document type:
Zeitschriftenaufsatz
Author(s):
Deán-Ben, Xosé Luís; Weidenfeld, Ina; Degtyaruk, Oleksiy; Ntziachristos, Vasilis; Stiel, Andre C; Razansky, Daniel
Abstract:
Widespread metastasis is the major cause of death from melanoma and other types of cancer. At present, the dynamic aspects of the metastatic cascade remain enigmatic. The feasibility to track circulating melanoma cells deep within living intact organisms can greatly impact our knowledge on tumor metastasis, but existing imaging approaches lack the sensitivity, spatio-temporal resolution or penetration depth to capture flowing tumor cells over large fields of view within optically-opaque biologic...     »
Journal title:
Neoplasia
Journal title abbreviation:
Neoplasia
Year:
2020
Journal volume:
22
Journal issue:
9
Pages contribution:
441-446
Fulltext / DOI:
doi:10.1016/j.neo.2020.06.008
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/32653834
WWW:
https://www.sciencedirect.com/science/article/pii/S1476558620301305
Print-ISSN:
1522-8002
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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