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Titel:

Visualizing cortical response to optogenetic stimulation and sensory inputs using multispectral handheld optoacoustic imaging.

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Ovsepian, Saak V; Jiang, Yuanyuan; Sardella, Thomas C P; Malekzadeh-Najafabadi, Jaber; Burton, Neal C; Yu, Xin; Ntziachristos, Vasilis
Abstract:
To date, the vast majority of intra-vital neuroimaging systems applied in clinic and diagnostics is stationary with a rigid scanning element, requires specialized facilities and costly infrastructure. Here, we describe a simple yet radical approach for optoacoustic (photoacoustic) brain imaging in vivo using a light-weight handheld probe. It enables multispectral video-rate visualization of hemoglobin gradient changes in the cortex of adult rats induced by whisker and forelimb sensory inputs, as...     »
Zeitschriftentitel:
Photoacoustics
Zeitschriftentitel:
Photoacoustics
Jahr:
2020
Band / Volume:
17
Volltext / DOI:
doi:10.1016/j.pacs.2019.100153
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/32154103
WWW:
https://www.sciencedirect.com/science/article/pii/S221359791930076X
Print-ISSN:
2213-5979
TUM Einrichtung:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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