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Title:

Visualizing cellularity and angiogenesis in newly-diagnosed glioblastoma with diffusion and perfusion MRI and FET-PET imaging.

Document type:
Journal Article
Author(s):
Liesche-Starnecker, Friederike; Prokop, Georg; Yakushev, Igor; Preibisch, Christine; Delbridge, Claire; Meyer, Hanno S; Aftahy, Kaywan; Barz, Melanie; Meyer, Bernhard; Zimmer, Claus; Schlegel, Jürgen; Wiestler, Benedikt; Gempt, Jens
Abstract:
PURPOSE: Combining imaging modalities has become an essential tool for assessment of tumor biology in glioblastoma (GBM) patients. Aim of this study is to understand how tumor cellularity and neovascularization are reflected in O-(2-[18F]fluoroethyl)-L-tyrosine positron emission tomography ([18F] FET PET) and magnetic resonance imaging (MRI) parameters, including cerebral blood volume (CBV), fractional anisotropy (FA) and mean diffusivity (MD). METHODS: In this prospective cohort, 162 targeted b...     »
Journal title abbreviation:
EJNMMI Res
Year:
2021
Journal volume:
11
Journal issue:
1
Fulltext / DOI:
doi:10.1186/s13550-021-00817-3
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34398358
Print-ISSN:
2191-219X
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer); Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Nuklearmedizin; Neurochirurgische Klinik und Poliklinik
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