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Title:

PSMA PET Imaging in Glioblastoma: A Preclinical Evaluation and Theranostic Outlook.

Document type:
Journal Article
Author(s):
Kirchner, Maximilian A; Holzgreve, Adrien; Brendel, Matthias; Orth, Michael; Ruf, Viktoria C; Steiger, Katja; Pötter, Dennis; Gold, Lukas; Unterrainer, Marcus; Mittlmeier, Lena M; Barci, Enio; Kälin, Roland E; Glass, Rainer; Lindner, Simon; Kaiser, Lena; Maas, Jessica; von Baumgarten, Louisa; Ilhan, Harun; Belka, Claus; Notni, Johannes; Bartenstein, Peter; Lauber, Kirsten; Albert, Nathalie L
Abstract:
Background: Prostate specific membrane antigen (PSMA) PET imaging has recently gained attention in glioblastoma (GBM) patients as a potential theranostic target for PSMA radioligand therapy. However, PSMA PET has not yet been established in a murine GBM model. Our goal was to investigate the potential of PSMA PET imaging in the syngeneic GL261 GBM model and to give an outlook regarding the potential of PMSA radioligand therapy in this model. Methods: We performed an 18F-PSMA-1007 PET study in th...     »
Journal title abbreviation:
Front Oncol
Year:
2021
Journal volume:
11
Fulltext / DOI:
doi:10.3389/fonc.2021.774017
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34869017
Print-ISSN:
2234-943X
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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