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Titel:

Stroma composition and proliferative activity are related to therapy response in neoadjuvant treated pancreatic ductal adenocarcinoma.

Dokumenttyp:
Journal Article
Autor(en):
Haeberle, Lena; Insilla, Andrea Cacciato; Kapp, Anne-Christine; Steiger, Katja; Schlitter, Anna Melissa; Konukiewitz, Björn; Demir, Ihsan Ekin; Friess, Helmut; Esposito, Irene
Abstract:
BACKGROUND: Tumor regression grading (TRG) based on histopathology is the main tool to assess therapy effects after neoadjuvant therapy (NAT) of pancreatic ductal adenocarcinoma (PDAC). However, reliable markers to distinguish therapy effects from pre-existing tumor features are lacking. The aim of this study was the characterization of PDAC after NAT, focusing on the stroma. MATERIAL AND METHODS: Tissue samples from patients resected for PDAC after NAT (n=27) were analyzed. TRG was assessed usi...     »
Zeitschriftentitel:
Histol Histopathol
Jahr:
2021
Band / Volume:
36
Heft / Issue:
7
Seitenangaben Beitrag:
733-742
Volltext / DOI:
doi:10.14670/HH-18-332
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33769550
Print-ISSN:
0213-3911
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Chirurgie
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