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Title:

Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives.

Document type:
Journal Article; Review
Author(s):
Poller, Wolfgang; Dimmeler, Stefanie; Heymans, Stephane; Zeller, Tanja; Haas, Jan; Karakas, Mahir; Leistner, David-Manuel; Jakob, Philipp; Nakagawa, Shinichi; Blankenberg, Stefan; Engelhardt, Stefan; Thum, Thomas; Weber, Christian; Meder, Benjamin; Hajjar, Roger; Landmesser, Ulf
Abstract:
Recent research has demonstrated that the non-coding genome plays a key role in genetic programming and gene regulation during development as well as in health and cardiovascular disease. About 99% of the human genome do not encode proteins, but are transcriptionally active representing a broad spectrum of non-coding RNAs (ncRNAs) with important regulatory and structural functions. Non-coding RNAs have been identified as critical novel regulators of cardiovascular risk factors and cell functions...     »
Journal title abbreviation:
Eur Heart J
Year:
2018
Journal volume:
39
Journal issue:
29
Pages contribution:
2704-2716
Fulltext / DOI:
doi:10.1093/eurheartj/ehx165
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28430919
Print-ISSN:
0195-668X
TUM Institution:
Institut für Pharmakologie und Toxikologie
 BibTeX