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Title:

The basophil activation test differentiates between patients with alpha-gal syndrome and asymptomatic alpha-gal sensitization.

Document type:
Journal Article
Author(s):
Mehlich, Jana; Fischer, Jörg; Hilger, Christiane; Swiontek, Kyra; Morisset, Martine; Codreanu-Morel, Françoise; Schiener, Maximilian; Blank, Simon; Ollert, Markus; Darsow, Ulf; Biedermann, Tilo; Eberlein, Bernadette
Abstract:
Galactose-alpha-1,3-galactose (alpha-gal) syndrome is characterized by the presence of serum specific IgE antibodies to alpha-gal and delayed type I allergic reactions to the carbohydrate alpha-gal after consumption of mammalian (red) meat products and drugs of mammalian origin. Diagnostics currently rely on patient history, skin tests, determination of serum specific IgE antibodies, and oral food or drug challenges.We sought to assess the utility of different basophil parameters (basophil react...     »
Journal title abbreviation:
J Allergy Clin Immunol
Year:
2019
Journal volume:
143
Journal issue:
1
Pages contribution:
182-189
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jaci.2018.06.049
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30125663
Print-ISSN:
0091-6749
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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