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Title:

Bacterial proteases in {IBD} and {IBS}.

Document type:
Zeitschriftenaufsatz
Author(s):
Steck, Natalie; Mueller, Kerstin; Schemann, Michael; Haller, Dirk
Abstract:
Proteases play a decisive role in health and disease. They fulfil diverse functions and have been associated with the pathology of gastrointestinal disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). The current knowledge focuses on host-derived proteases including matrix metalloproteinases, various serine proteases and cathepsins. The possible contribution of bacterial proteases has been largely ignored in the pathogenesis of IBD and IBS, although there is in...     »
Keywords:
Sensitivity and Specificity, Humans, Female, Male, Bacterial Physiological Phenomena, Disease Susceptibility, Inflammatory Bowel Diseases/*enzymology/*microbiology, Irritable Bowel Syndrome/*enzymology/*microbiology, Peptide Hydrolases/analysis/*metabolism, Risk Assessment
Journal title:
Gut
Year:
2012
Journal volume:
61
Month:
nov
Journal issue:
11
Pages contribution:
1610--1618
Language:
eng
Fulltext / DOI:
doi:10.1136/gutjnl-2011-300775
Print-ISSN:
1468-3288 0017-5749
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