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Titel:

Tissue-specific tumorigenesis: context matters.

Dokumenttyp:
Journal Article; Review; Review
Autor(en):
Schneider, Günter; Schmidt-Supprian, Marc; Rad, Roland; Saur, Dieter
Abstract:
How can we treat cancer more effectively? Traditionally, tumours from the same anatomical site are treated as one tumour entity. This concept has been challenged by recent breakthroughs in cancer genomics and translational research that have enabled molecular tumour profiling. The identification and validation of cancer drivers that are shared between different tumour types, spurred the new paradigm to target driver pathways across anatomical sites by off-label drug use, or within so-called bask...     »
Zeitschriftentitel:
Nat Rev Cancer
Jahr:
2017
Band / Volume:
17
Heft / Issue:
4
Seitenangaben Beitrag:
239-253
Sprache:
eng
Volltext / DOI:
doi:10.1038/nrc.2017.5
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28256574
Print-ISSN:
1474-175X
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Professur für Translationale gastroenterologische Onkologie (Prof. Rad)
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