Benutzer: Gast  Login
Titel:

Engineering an orchestrated release avalanche from hydrogels using DNA-nanotechnology

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Kimna, Ceren; Lieleg, Oliver
Abstract:
Most medical therapies require repeated, sequential administration of therapeutic agents in well-defined intervals and over extended time windows. Typically, the patient is in charge of applying the individual drug doses, and insufficient patient compliance reduces the efficiency of the treatment. Therefore, the development of a smart delivery mechanism releasing therapeutic agents in a pre-defined, time-controlled fashion would be beneficial for many medical treatments. Here, we present a DNA-m...     »
Stichworte:
DNA linker, Drug delivery, Nanoparticles, Sequential release
Zeitschriftentitel:
Journal of Controlled Release
Jahr:
2019
Band / Volume:
304
Seitenangaben Beitrag:
19-28
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1016/j.jconrel.2019.04.028
WWW:
https://www.sciencedirect.com/science/article/pii/S0168365919302287
Verlag / Institution:
Elsevier BV
E-ISSN:
0168-3659
Publikationsdatum:
01.06.2019
TUM Einrichtung:
Fachgebiet für Biomechanik
 BibTeX