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Titel:

One-Step Purification of Microbially Produced Hydrophobic Terpenes via Process Chromatography

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Grozdev L, Kaiser J, Berensmeier S:
Abstract:
Novel and existing terpenes are already being produced by genetically modified microorganisms, leading to new process challenges for the isolation and purification of these terpenes. Here, eight different chromatographic resins were characterized for the packed bed adsorption of the model terpene β-caryophyllene, showing their applicability on an Escherichia coli fermentation mixture. The polystyrenic Rensa® RP (Ø 50 μm) shows the highest affinity, with a maximum capacity of >100 g L−1 and the b...     »
Stichworte:
terpenes, preparative chromatography, purification, fermentation, process development and integration, β-caryophyllene
Zeitschriftentitel:
Front. Bioeng. Biotechnol.
Jahr:
2019
Jahr / Monat:
2019-07
Nachgewiesen in:
Scopus
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.3389/fbioe.2019.00185
WWW:
www.frontiersin.org/articles/10.3389/fbioe.2019.00185/full
TUM Einrichtung:
Professur für Selektive Trenntechnik
Eingabe:
09.10.2019
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