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Titel:

Ultra-flexible nanowire array for label- and distortion-free cellular force tracking

Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
Paulitschke, P.; Keber, F.; Lebedev, A.; Stephan, J.; Lorenz, B.; Haselmann, S.; Heinrich, D.; Weig, E.M.
Abstract:
Living cells interact with their immediate environment by exerting mechanical forces, which regulate important cell functions. Elucidation of such force patterns yields deep insights into the physics of life. Here we present a top-down nanostructured, ultraflexible nanowire array biosensor capable of probing cell-induced forces. Its universal building block, an inverted conical semiconductor nanowire, greatly enhances both the functionality and the sensitivity of the device. In contrast to exist...     »
Stichworte:
Nanowire array spring constant cellular force tracking Dictyostelium discoideum label-free biosensing optical distortions
Zeitschriftentitel:
Nano Lett. 19, 4, 2207–2214 2019-04
Jahr:
2019
Jahr / Monat:
2019-04
Quartal:
2. Quartal
Monat:
Apr
Sprache:
en
Volltext / DOI:
doi:10.1021/acs.nanolett.8b02568
WWW:
https://pubs.acs.org/doi/10.1021/acs.nanolett.8b02568
Verlag / Institution:
American Chemical Society ACS Publictions
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