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Title:

Does a Hypertrophying Muscle Fibre Reprogramme its Metabolism Similar to a Cancer Cell?

Document type:
Zeitschriftenaufsatz
Author(s):
Wackerhage, Henning; Vechetti, Ivan J.; Baumert, Philipp; Gehlert, Sebastian; Becker, Lore; Jaspers, Richard T.; de Angelis, Martin Hrabě
Abstract:
In 1924, Otto Warburg asked “How does the metabolism of a growing tissue differ from that of a non-growing tissue?” Currently, we know that proliferating healthy and cancer cells reprogramme their metabolism. This typically includes increased glucose uptake, glycolytic flux and lactate synthesis. A key function of this reprogramming is to channel glycolytic intermediates and other metabolites into anabolic reactions such as nucleotide-RNA/DNA synthesis, amino acid-protein synthesis and the synth...     »
Dewey Decimal Classification:
500 Naturwissenschaften; 610 Medizin und Gesundheit
Journal title:
Sports Medicine
Year:
2022
Year / month:
2022-04
Quarter:
2. Quartal
Month:
Apr
Covered by:
Web of Science
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.1007/s40279-022-01676-1
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/35460513
Publisher:
Springer Science and Business Media LLC
E-ISSN:
0112-16421179-2035
Impact Factor:
8,551
Scimago Quartil:
Q1
Notes:
SCImago Journal &  Country Rank
Status:
Erstveröffentlichung
Date of publication:
23.04.2022
Semester:
SS 22
TUM Institution:
Sportbiologie
Format:
Bild/Text
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