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Title:

Effect of an eight-week high-intensity interval training programme on circulating sphingolipid levels in middle-aged adults at elevated cardiometabolic risk (SphingoFIT)—Protocol for a randomised controlled exercise trial

Document type:
Zeitschriftenaufsatz
Author(s):
Carrard, Justin; Hofer, Manuel; Prechtl, Luisa; Fleischlin, Eva; Huber, Manuel; Gallart-Ayala, Hector; Teav, Tony; Infanger, Denis; Höchsmann, Christoph; Koehler, Karsten; Hinrichs, Timo; Hanssen, Henner; Ivanisevic, Julijana; Schmidt-Trucksäss, Arno
Abstract:
Introduction: Evidence indicates that sphingolipid accumulation drives complex molecular alterations promoting cardiometabolic diseases. Clinically, it was shown that sphingolipids predict cardiometabolic risk independently of and beyond traditional biomarkers such as low-density lipoprotein cholesterol. To date, little is known about therapeutic modalities to lower sphingolipid levels. Exercise, a powerful means to prevent and treat cardiometabolic diseases, is a promising modality to mitigate...     »
Dewey Decimal Classification:
570 Biowissenschaften, Biologie; 610 Medizin und Gesundheit; 790 Sport, Spiele, Unterhaltung
Journal title:
PLOS ONE
Year:
2024
Journal volume:
19
Journal issue:
5
Pages contribution:
e0302477
Reviewed:
ja
Language:
en
Fulltext / DOI:
doi:10.1371/journal.pone.0302477
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/38717997
Publisher:
Public Library of Science (PLoS)
E-ISSN:
1932-6203
Impact Factor:
3,7
Scimago Quartil:
Q1
Submitted:
30.03.2024
Accepted:
03.04.2024
Date of publication:
08.05.2024
Semester:
SS 24
TUM Institution:
Professur für Bewegung, Ernährung und Gesundheit
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