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Title:

Meeting the Challenges of High-Dimensional Single-Cell Data Analysis in Immunology.

Document type:
Journal Article; Review
Author(s):
Palit, Subarna; Heuser, Christoph; de Almeida, Gustavo P; Theis, Fabian J; Zielinski, Christina E
Abstract:
Recent advances in cytometry have radically altered the fate of single-cell proteomics by allowing a more accurate understanding of complex biological systems. Mass cytometry (CyTOF) provides simultaneous single-cell measurements that are crucial to understand cellular heterogeneity and identify novel cellular subsets. High-dimensional CyTOF data were traditionally analyzed by gating on bivariate dot plots, which are not only laborious given the quadratic increase of complexity with dimension bu...     »
Journal title abbreviation:
Front Immunol
Year:
2019
Journal volume:
10
Fulltext / DOI:
doi:10.3389/fimmu.2019.01515
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31354705
Print-ISSN:
1664-3224
TUM Institution:
Institut für Virologie
 BibTeX