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Titel:

The CARD9-Associated C-Type Lectin, Mincle, Recognizes La Crosse Virus (LACV) but Plays a Limited Role in Early Antiviral Responses against LACV.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Monteiro, João T; Schön, Kathleen; Ebbecke, Tim; Goethe, Ralph; Ruland, Jürgen; Baumgärtner, Wolfgang; Becker, Stefanie C; Lepenies, Bernd
Abstract:
La Crosse virus (LACV) is a mosquito-transmitted arbovirus and the main cause of virus-mediated neurological diseases in children. To date, little is known about the role of C-type lectin receptors (CLRs)-an important class of pattern recognition receptors-in LACV recognition. DC-SIGN remains the only well-described CLR that recognizes LACV. In this study, we investigated the role of additional CLR/LACV interactions. To this end, we applied a flow-through chromatography method for the purificati...     »
Zeitschriftentitel:
Viruses
Jahr:
2019
Band / Volume:
11
Heft / Issue:
3
Volltext / DOI:
doi:10.3390/v11030303
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30917612
Print-ISSN:
1999-4915
TUM Einrichtung:
Institut für Klinische Chemie und Pathobiochemie
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