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Title:

Fluorescence imaging of invasive head and neck carcinoma cells with integrin ?v?6-targeting RGD-peptides: an approach to a fluorescence-assisted intraoperative cytological assessment of bony resection margins.

Document type:
Journal Article
Author(s):
Nieberler, M; Reuning, U; Kessler, H; Reichart, F; Weirich, G; Wolff, K-D
Abstract:
We assessed the use of peptides containing arginylglycylaspartic acid (RGD) that target integrin ?v?6 as a potential approach for a fluorescence-assisted intraoperative cytological assessment of bony resection margins (F-AICAB) in patients who had bone-infiltrating squamous cell carcinoma (SCC) of the head and neck. This was assessed to demarcate invasive carcinoma cells that stained for ?v?6. Specimens from bony resection margins (n=362) were defined as either malignant or benign according to t...     »
Journal title abbreviation:
Br J Oral Maxillofac Surg
Year:
2018
Journal volume:
56
Journal issue:
10
Pages contribution:
972-978
Language:
eng
Fulltext / DOI:
doi:10.1016/j.bjoms.2018.11.003
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30502043
Print-ISSN:
0266-4356
TUM Institution:
Frauenklinik und Poliklinik; Institut für Allgemeine Pathologie und Pathologische Anatomie; Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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