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Titel:

Evidence for Myelin Sheath Remodeling in the CNS Revealed by In Vivo Imaging

Dokumenttyp:
Article
Autor(en):
Auer, Franziska; Vagionitis, Stavros; Czopka, Tim
Abstract:
The length of myelin sheaths affects conduction speed along axons and information propagation. It has recently become clear that myelin may be adaptively modified to modulate circuit function, implying that length remodeling of myelin sheaths should occur. However, direct evidence for such events is lacking. We have investigated how myelination patterns are formed, maintained, and remodeled using long-term imaging and myelin ablation in zebrafish. We demonstrate that length differences between m...     »
Zeitschriftentitel:
Curr Biol
Jahr:
2018
Band / Volume:
28
Heft / Issue:
4
Seitenangaben Beitrag:
549-+
Volltext / DOI:
doi:10.1016/j.cub.2018.01.017
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29429620
Print-ISSN:
0960-9822
TUM Einrichtung:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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