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Title:

Evidence for Myelin Sheath Remodeling in the CNS Revealed by In Vivo Imaging

Document type:
Article
Author(s):
Auer, Franziska; Vagionitis, Stavros; Czopka, Tim
Abstract:
The length of myelin sheaths affects conduction speed along axons and information propagation. It has recently become clear that myelin may be adaptively modified to modulate circuit function, implying that length remodeling of myelin sheaths should occur. However, direct evidence for such events is lacking. We have investigated how myelination patterns are formed, maintained, and remodeled using long-term imaging and myelin ablation in zebrafish. We demonstrate that length differences between m...     »
Journal title abbreviation:
Curr Biol
Year:
2018
Journal volume:
28
Journal issue:
4
Pages contribution:
549-+
Fulltext / DOI:
doi:10.1016/j.cub.2018.01.017
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/29429620
Print-ISSN:
0960-9822
TUM Institution:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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