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Titel:

Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand

Dokumenttyp:
Article
Autor(en):
Almeida, Rafael G.; Pan, Simon; Cole, Katy L. H.; Williamson, Jill M.; Early, Jason J.; Czopka, Tim; Klingseisen, Anna; Chan, Jonah R.; Lyons, David A.
Abstract:
The correct targeting of myelin is essential for nervous system formation and function. Oligodendrocytes in the CNS myelinate some axons, but not others, and do not myelinate structures including cell bodies and dendrites [1]. Recent studies indicate that extrinsic signals, such as neuronal activity [2, 3] and cell adhesion molecules [4], can bias myelination toward some axons and away from cell bodies and dendrites, indicating that, in vivo, neuronal and axonal cues regulate myelin targeting. I...     »
Zeitschriftentitel:
Curr Biol
Jahr:
2018
Band / Volume:
28
Heft / Issue:
8
Seitenangaben Beitrag:
1296-+
Volltext / DOI:
doi:10.1016/j.cub.2018.02.068
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29628374
Print-ISSN:
0960-9822
TUM Einrichtung:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)
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