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Titel:

Development of photosynthetic sutures for the local delivery of oxygen and recombinant growth factors in wounds.

Dokumenttyp:
Journal Article
Autor(en):
Centeno-Cerdas, Carolina; Jarquín-Cordero, Montserrat; Chávez, Myra Noemi; Hopfner, Ursula; Holmes, Christopher; Schmauss, Daniel; Machens, Hans-Günther; Nickelsen, Jörg; Egaña, José Tomás
Abstract:
Surgical sutures represent the gold standard for wound closure, however, their main purpose is still limited to a mechanical function rather than playing a bioactive role. Since oxygen and pro-regenerative growth factors have been broadly described as key players for the healing process, in this study we evaluated the feasibility of generating photosynthetic sutures that, in addition to mechanical fixation, could locally and stably release oxygen and recombinant human growth factors (VEGF, PDGF-...     »
Zeitschriftentitel:
Acta Biomater
Jahr:
2018
Band / Volume:
81
Seitenangaben Beitrag:
184-194
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.actbio.2018.09.060
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30287280
Print-ISSN:
1742-7061
TUM Einrichtung:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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