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Dokumenttyp:
Journal Article
Autor(en):
Mokrousov, Maksim D; Novoselova, Marina V; Nolan, Jackie; Harrington, Walter; Rudakovskaya, Polina; Bratashov, Daniil N; Galanzha, Ekaterina I; Fuenzalida-Werner, Juan Pablo; Yakimov, Boris P; Nazarikov, Gleb; Drachev, Vladimir P; Shirshin, Evgeny A; Ntziachristos, Vasilis; Stiel, Andre C; Zharov, Vladimir P; Gorin, Dmitry A
Titel:
Amplification of photoacoustic effect in bimodal polymer particles by self-quenching of indocyanine green.
Abstract:
A new type of bimodal contrast agent was made that is based on the self-quenching of indocyanine green (ICG) encapsulated in a biocompatible and biodegradable polymer shell. The increasing of a local ICG concentration that is necessary for the obtaining of self-quenching effect was achieved by freezing-induced loading and layer-by-layer assembly. As a result, an efficient photoacoustic(optoacoustic)/fluorescent contrast agent based on composite indocyanine green/polymer particles was successfull...     »
Zeitschriftentitel:
Biomed Opt Express
Jahr:
2019
Band / Volume:
10
Heft / Issue:
9
Seitenangaben Beitrag:
4775-4789
Volltext / DOI:
doi:10.1364/BOE.10.004775
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/31565524
Print-ISSN:
2156-7085
TUM Einrichtung:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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