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Title:

ALDH1 - A new immunohistochemical diagnostic marker for Schwann cell-derived tumors.

Document type:
Journal Article
Author(s):
Liesche, Friederike; Griessmair, Michael; Barz, Melanie; Gempt, Jens; Schlegel, Jürgen
Abstract:
Although Schwann cell-derived tumors show typical histological features, the broad variety of spindle cell tumors that exist can impede the diagnostic procedure. In this study, we present aldehyde dehydrogenase 1 (ALDH1) as a new, viable diagnostic marker for Schwann cell tumors. Protein expression was examined by immunohistochemistry in schwannomas, neurofibromas, and malignant peripheral nerve sheath tumors (MPNST) as well as in non-neoplastic peripheral nerve sheath specimens. Meningiomas and...     »
Journal title abbreviation:
Clin Neuropathol
Year:
2019
Journal volume:
38
Journal issue:
4
Pages contribution:
168-173
Fulltext / DOI:
doi:10.5414/NP301190
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31131824
Print-ISSN:
0722-5091
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Neurochirurgische Klinik und Poliklinik
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