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Title:

BRAF V600E and Retinoic Acid in Radioiodine-Refractory Papillary Thyroid Cancer.

Document type:
Journal Article
Author(s):
Groener, Jan Benedikt; Gelen, Debora; Mogler, Carolin; Herpel, Esther; Toth, Csaba; Kender, Zoltan; Peichl, Marco; Haufe, Sabine; Haberkorn, Uwe; Sulaj, Alba; Zemva, Johanna; Kopf, Stefan; Nawroth, Peter Paul; Brune, Maik; Rudofsky, Gottfried
Abstract:
Radioiodine refractoriness in differentiated thyroid cancer remains an unsolved therapeutic problem. Response to retinoids might depend on specific genetic markers. In this retrospective analysis, associations between BRAF V600E and clinical outcomes after redifferentiation with retinoic acid (RA) and radioiodine therapy (RIT) were investigated. Thirteen patients with radioiodine-refractory (RAI-R) papillary thyroid cancer (PTC) were treated with 13-cis-RA followed by iodine-131 treatment at the...     »
Journal title abbreviation:
Horm Metab Res
Year:
2019
Journal volume:
51
Journal issue:
1
Pages contribution:
69-75
Language:
eng
Fulltext / DOI:
doi:10.1055/a-0765-9078
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30396219
Print-ISSN:
0018-5043
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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