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Title:

An orthogonal proteomic survey uncovers novel Zika virus host factors.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Scaturro, Pietro; Stukalov, Alexey; Haas, Darya A; Cortese, Mirko; Draganova, Kalina; P?aszczyca, Anna; Bartenschlager, Ralf; Götz, Magdalena; Pichlmair, Andreas
Abstract:
Zika virus (ZIKV) has recently emerged as a global health concern owing to its widespread diffusion and its association with severe neurological symptoms and microcephaly in newborns. However, the molecular mechanisms that are responsible for the pathogenicity of ZIKV remain largely unknown. Here we use human neural progenitor cells and the neuronal cell line SK-N-BE2 in an integrated proteomics approach to characterize the cellular responses to viral infection at the proteome and phosphoproteom...     »
Journal title abbreviation:
Nature
Year:
2018
Journal volume:
561
Journal issue:
7722
Pages contribution:
253-257
Fulltext / DOI:
doi:10.1038/s41586-018-0484-5
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/30177828
Print-ISSN:
0028-0836
TUM Institution:
Institut für Virologie
 BibTeX