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Document type:
Journal Article 
Author(s):
Whelan, Jeremy; Le Deley, Marie-Cécile; Dirksen, Uta; Le Teuff, Gwénaël; Brennan, Bernadette; Gaspar, Nathalie; Hawkins, Douglas S; Amler, Susanne; Bauer, Sebastian; Bielack, Stefan; Blay, Jean-Yves; Burdach, Stefan; Castex, Marie-Pierre; Dilloo, Dagmar; Eggert, Angelika; Gelderblom, Hans; Gentet, Jean-Claude; Hartmann, Wolfgang; Hassenpflug, Wolf-Achim; Hjorth, Lars; Jimenez, Marta; Klingebiel, Thomas; Kontny, Udo; Kruseova, Jarmila; Ladenstein, Ruth; Laurence, Valérie; Lervat, Cyril; Marec-Ber...    »
 
Title:
High-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma: Results of Euro-E.W.I.N.G.99 and Ewing-2008. 
Abstract:
Purpose For over 30 years, the place of consolidation high-dose chemotherapy in Ewing sarcoma (ES) has been controversial. A randomized study was conducted to determine whether consolidation high-dose chemotherapy improved survival in patients with localized ES at high risk for relapse. Methods Randomization between busulfan and melphalan (BuMel) or standard chemotherapy (vincristine, dactinomycin, and ifosfamide [VAI], seven courses) was offered to patients if they were younger than 50 years of...    »
 
Journal title abbreviation:
J Clin Oncol 
Year:
2018 
Fulltext / DOI:
Print-ISSN:
0732-183X 
TUM Institution:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin